wife
妻(つま)、夫妻(ふさい)
wife, husband
On-reading (サイ) is used in compounds; kun-reading (つま) is used standalone or with okurigana.
From the JLP Quiz question bank — the word in the form it is actually tested in.
「妻」の読み方は?
Answer: つま
週末は家族と過ごすことが多く、子供と公園で遊んだり、妻と買い物に行ったりします。
Answer: 7時15分